Assay Report Card

Basic Information

ID: ALA5145932

Type: Binding

Description: Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis at 100 nM incubated for 1 hrs followed by 13C-addition of 13C-oleic acid pre-complexed with fatty acid free BSA for 6 hrs by LC/MS/MS analysis

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
525.566.056.05
482.495.485.48