Assay Report Card

Basic Information

ID: ALA5145998

Type: Functional

Description: Invivo inhibition of DGAT1 in in C57BL/6 mouse model of acute lipid challenge assessed as reduction in chylomicron derived plasma triglyceride excursion at 3 to 10 mg/kg, po as corn oil bolus by Oral lipid tolerance test relative to control

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
526.544.994.99
484.463.823.82