Basic Information
ID: ALA5146032
Type: Binding
Description: Inhibition of human CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr followed by substrate addition and measured after 2 hrs by malachite green reagent based colorimetric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5146032
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 442.73 | 7.00 | 7.00 |
| 454.70 | 7.30 | 7.30 |
| 472.71 | 6.06 | 6.06 |
| 440.71 | 7.20 | 7.20 |
| 425.23 | -1.64 | -1.64 |
| 555.80 | 6.91 | 6.91 |
| 582.87 | 7.66 | 7.66 |
| 612.90 | 7.16 | 7.16 |
| 567.86 | 8.72 | 8.72 |
| 568.84 | 7.14 | 7.14 |
| 582.87 | 7.48 | 7.48 |
| 541.82 | 8.23 | 8.23 |
| 553.83 | 8.33 | 8.33 |
| 539.80 | 7.99 | 7.99 |
| 543.79 | 6.82 | 6.82 |