Assay Report Card

Basic Information

ID: ALA5146036

Type: Binding

Description: Potency index, ratio of betulinic acid IC50 to test compound IC50 for inhibition of human CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr followed by substrate addition and measured after 2 hrs by malachite green reagent based colorimetric assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
567.868.728.72
541.828.238.23