Basic Information
ID: ALA5146944
Type: Binding
Description: Covalent inhibition of recombinant recombinant human GST-tagged JAK3(781 to 1124 residues) expressed in baculovirus expression system incubated for 1 hr in the presence of ATP by FRET based Z'-LYTE assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK3(ALA2148)
Document: ALA5143636
Covalent inhibition of recombinant recombinant human GST-tagged JAK3(781 to 1124 residues) expressed in baculovirus expression system incubated for 1 hr in the presence of ATP by FRET based Z'-LYTE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5146944
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 429.48 | 3.94 | 3.94 |
| 401.43 | 2.44 | 2.44 |
| 539.64 | 3.78 | 3.78 |
| 553.62 | 3.39 | 3.39 |
| 539.64 | 3.86 | 3.86 |
| 565.68 | 4.35 | 4.35 |
| 484.56 | 3.17 | 3.17 |
| 553.67 | 4.25 | 4.25 |
| 527.63 | 3.71 | 3.71 |
| 427.46 | 3.72 | 3.72 |
| 427.46 | 3.72 | 3.72 |
| 567.69 | 4.42 | 4.42 |
| 553.67 | 4.03 | 4.03 |
| 525.61 | 3.47 | 3.47 |
| 441.49 | 4.11 | 4.11 |
| 495.59 | 3.46 | 3.46 |
| 427.46 | 3.72 | 3.72 |
| 445.48 | 2.55 | 2.55 |
| 524.63 | 4.53 | 4.53 |
| 431.46 | 1.90 | 1.90 |