Assay Report Card

Basic Information

ID: ALA5147345

Type: Binding

Description: Inhibition of RIPK1-RIPK3-MLKL pathway in TSZ induced human HT-29 cells assessed as reduction in necrosome formation at 10 nM measured after 6 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HT-29

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
407.502.362.36