Assay Report Card

Basic Information

ID: ALA5147346

Type: Functional

Description: Anti-necroptic activity against mTNFalpha-induced systemic inflammatory response syndrome C57BL/6J mouse model assessed as protection of body temperature pretreated with compound at 5 to 15 mg/kg, IG administered as single dose followed by mTNFalpha injection measured after 2 to 3 hrs

Organism: Mus musculus

Strain: C57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
407.502.362.36