Basic Information
ID: ALA5147366
Type: Binding
Description: Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5147366
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.55 | 4.10 | 4.10 |
| 447.58 | 4.49 | 4.49 |
| 432.52 | 4.01 | 4.01 |
| 448.52 | 2.98 | 2.98 |
| 446.55 | 4.40 | 4.40 |
| 420.51 | 3.87 | 3.87 |
| 420.51 | 3.87 | 3.87 |
| 450.51 | 3.96 | 3.96 |
| 482.56 | 2.61 | 2.61 |
| 448.52 | 2.98 | 2.98 |
| 449.55 | 3.34 | 3.34 |