Basic Information
ID: ALA5147694
Type: Binding
Description: Inhibition of recombinant human Nav 1.7 expressed in HEK293F cells incubated for 3 mins by FRET based membrane potential assay
Organism: Homo sapiens
Cell type: HEK293F
Subcellular Fraction: Cell membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5147694
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.37 | 2.62 | 2.62 |
| 402.38 | 3.49 | 3.49 |
| 384.39 | 3.41 | 3.41 |
| 417.34 | 3.49 | 3.49 |
| 387.36 | 4.68 | 4.68 |
| 348.41 | 2.81 | 2.81 |
| 405.35 | 4.62 | 4.62 |
| 403.36 | 2.88 | 2.88 |
| 418.38 | 3.37 | 3.37 |
| 401.39 | 4.09 | 4.09 |
| 403.36 | 2.88 | 2.88 |
| 403.36 | 3.69 | 3.69 |
| 409.31 | 4.53 | 4.53 |
| 373.33 | 4.29 | 4.29 |
| 352.37 | 2.61 | 2.61 |
| 439.42 | 3.22 | 3.22 |
| 405.35 | 4.67 | 4.67 |
| 470.37 | 4.42 | 4.42 |
| 451.43 | 3.31 | 3.31 |
| 387.36 | 4.72 | 4.72 |
| 402.38 | 3.49 | 3.49 |
| 402.38 | 3.49 | 3.49 |
| 375.43 | 3.28 | 3.28 |
| 358.40 | 2.94 | 2.94 |
| 403.36 | 3.96 | 3.96 |
| 423.34 | 4.97 | 4.97 |
| 405.35 | 4.62 | 4.62 |
| 484.40 | 4.76 | 4.76 |
| 465.45 | 3.37 | 3.37 |
| 372.43 | 2.73 | 2.73 |
| 389.41 | 3.14 | 3.14 |
| 432.40 | 3.25 | 3.25 |
| 352.35 | 1.40 | 1.40 |
| 371.44 | 3.55 | 3.55 |
| 402.45 | 3.05 | 3.05 |
| 364.41 | 2.23 | 2.23 |
| 431.41 | 4.83 | 4.83 |
| 357.46 | 4.03 | 4.03 |
| 378.43 | 2.57 | 2.57 |
| 376.37 | 1.88 | 1.88 |
| 387.44 | 4.29 | 4.29 |
| 402.41 | 2.24 | 2.24 |
| 378.39 | 1.76 | 1.76 |
| 373.46 | 4.15 | 4.15 |
| 363.42 | 3.81 | 3.81 |
| 446.43 | 3.59 | 3.59 |
| 373.46 | 4.76 | 4.76 |
| 446.39 | 2.78 | 2.78 |
| 388.43 | 2.71 | 2.71 |