Basic Information
ID: ALA5148065
Type: Functional
Description: Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence of IBMX by cAMP assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA5148065
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 625.57 | 7.16 | 7.16 |
| 593.56 | 6.68 | 6.68 |
| 567.52 | 5.33 | 5.33 |
| 551.52 | 6.22 | 6.22 |
| 623.58 | 6.45 | 6.45 |
| 581.54 | 5.99 | 5.99 |
| 609.55 | 5.76 | 5.76 |
| 595.57 | 6.33 | 6.33 |
| 593.56 | 6.68 | 6.68 |
| 595.53 | 5.67 | 5.67 |
| 583.49 | 5.99 | 5.99 |
| 623.58 | 6.45 | 6.45 |
| 611.55 | 6.77 | 6.77 |
| 637.58 | 7.31 | 7.31 |
| 625.57 | 7.16 | 7.16 |