Basic Information
ID: ALA5148367
Type: ADME
Description: Metabolic stability in Sprague-Dawley rat liver microsomes assessed as half life at 1 uM preincubated for 5 mins followed by NADPH addition and measured upto 60 mins by HPLC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5148367
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.76 | 7.04 | 7.04 |
| 573.64 | 6.94 | 6.94 |
| 561.75 | 7.22 | 7.22 |
| 519.67 | 6.23 | 6.23 |
| 505.64 | 5.92 | 5.92 |
| 651.70 | 8.04 | 8.04 |
| 615.72 | 7.76 | 7.76 |