Basic Information
ID: ALA5148416
Type: ADME
Description: Metabolic stability in Sprague-Dawley rat liver microsomes assessed as parent compound remaining at 1 uM measured after 30 mins in the presence of NADPH by LC-MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5148416
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 551.73 | 4.72 | 4.72 |
| 539.70 | 4.85 | 4.85 |
| 587.73 | 6.50 | 6.50 |
| 627.67 | 6.65 | 6.65 |
| 575.63 | 3.99 | 3.99 |
| 545.65 | 5.12 | 5.12 |
| 573.66 | 5.29 | 5.29 |
| 569.77 | 4.10 | 4.10 |
| 555.71 | 5.81 | 5.81 |
| 492.67 | 4.09 | 4.09 |
| 687.73 | 6.58 | 6.58 |
| 571.71 | 5.38 | 5.38 |
| 519.61 | 4.79 | 4.79 |
| 561.69 | 5.82 | 5.82 |
| 508.67 | 3.33 | 3.33 |
| 561.65 | 4.56 | 4.56 |
| 585.72 | 6.11 | 6.11 |
| 553.58 | 4.79 | 4.79 |
| 587.69 | 5.63 | 5.63 |
| 575.68 | 5.60 | 5.60 |
| 573.70 | 6.11 | 6.11 |
| 519.73 | 5.26 | 5.26 |
| 493.66 | 3.49 | 3.49 |
| 498.70 | 4.15 | 4.15 |
| 570.63 | 6.61 | 6.61 |
| 575.63 | 4.14 | 4.14 |
| 519.73 | 5.32 | 5.32 |
| 570.66 | 5.74 | 5.74 |
| 556.63 | 5.44 | 5.44 |
| 607.69 | 5.78 | 5.78 |
| 565.71 | 5.78 | 5.78 |
| 521.71 | 4.71 | 4.71 |
| 510.68 | 4.30 | 4.30 |
| 531.75 | 5.58 | 5.58 |
| 559.68 | 5.72 | 5.72 |
| 567.60 | 5.18 | 5.18 |
| 491.68 | 4.70 | 4.70 |
| 581.63 | 5.57 | 5.57 |
| 537.77 | 5.42 | 5.42 |
| 537.72 | 5.40 | 5.40 |
| 573.66 | 4.56 | 4.56 |
| 595.66 | 5.96 | 5.96 |
| 526.13 | 5.35 | 5.35 |
| 533.76 | 5.82 | 5.82 |
| 497.71 | 4.76 | 4.76 |
| 515.70 | 4.68 | 4.68 |