Basic Information
ID: ALA5148450
Type: Binding
Description: Inhibition of ERK activity in human MM121224 cells harboring BRAF V600E/NRAS Q61K mutant derived from melanoma patient by high-content screening microscopic analysis
Organism: Homo sapiens
Cell type: MM121224
Activity Charts
Bioactivity
Activity Types for Assay ALA5148450
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.35 | 2.91 | 2.91 |
| 344.32 | 2.90 | 2.90 |
| 360.32 | 2.60 | 2.60 |
| 330.29 | 2.59 | 2.59 |
| 346.29 | 2.30 | 2.30 |
| 360.32 | 2.60 | 2.60 |
| 416.43 | 2.13 | 2.13 |
| 386.40 | 1.77 | 1.77 |
| 360.32 | 2.60 | 2.60 |
| 400.43 | 2.43 | 2.43 |
| 416.43 | 2.13 | 2.13 |
| 400.43 | 2.43 | 2.43 |