Basic Information
ID: ALA5148460
Type: Toxicity
Description: Selectivity index, ratio of IC50 for human DHFR to IC50 for Trypanosoma brucei DHFR
Activity Charts
Bioactivity
Activity Types for Assay ALA5148460
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 317.36 | 2.35 | 2.35 |
| 436.48 | 1.22 | 1.22 |
| 450.50 | 1.25 | 1.25 |
| 421.47 | 0.53 | 0.53 |
| 437.46 | 0.62 | 0.62 |
| 480.53 | 0.61 | 0.61 |
| 422.45 | 1.13 | 1.13 |
| 436.48 | 1.22 | 1.22 |
| 494.56 | 1.00 | 1.00 |
| 474.53 | 1.82 | 1.82 |
| 371.40 | 2.43 | 2.43 |
| 363.30 | 1.53 | 1.53 |
| 464.53 | 1.64 | 1.64 |
| 463.50 | 2.69 | 2.69 |
| 454.52 | 1.30 | 1.30 |
| 436.48 | 1.36 | 1.36 |
| 450.50 | 1.15 | 1.15 |
| 417.47 | 3.02 | 3.02 |
| 526.60 | 2.82 | 2.82 |
| 493.57 | 0.24 | 0.24 |
| 474.53 | 1.25 | 1.25 |
| 493.57 | 4.59 | 4.59 |
| 392.47 | 1.85 | 1.85 |
| 295.31 | 0.51 | 0.51 |
| 478.56 | 2.03 | 2.03 |
| 479.55 | -0.01 | -0.01 |
| 399.46 | 2.84 | 2.84 |
| 373.42 | 2.67 | 2.67 |
| 414.47 | 2.17 | 2.17 |
| 403.45 | 2.67 | 2.67 |
| 478.56 | 2.03 | 2.03 |
| 464.53 | 1.64 | 1.64 |
| 444.50 | 1.81 | 1.81 |