Basic Information
ID: ALA5148523
Type: Binding
Description: Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]ZM241385 addition and measured after 1.5 hrs by TopCount scintillation counting method
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5148523
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.74 | 3.28 | 3.28 |
| 291.26 | 1.46 | 1.46 |
| 332.37 | 1.83 | 1.83 |
| 318.34 | 1.79 | 1.79 |
| 285.31 | 0.84 | 0.84 |
| 318.34 | 1.79 | 1.79 |
| 285.31 | 0.58 | 0.58 |
| 332.37 | 1.83 | 1.83 |
| 333.35 | 2.73 | 2.73 |
| 285.31 | 0.58 | 0.58 |
| 285.31 | 0.58 | 0.58 |
| 375.39 | 2.17 | 2.17 |
| 303.33 | 2.72 | 2.72 |
| 337.77 | 3.37 | 3.37 |
| 307.31 | 1.99 | 1.99 |
| 347.38 | 2.14 | 2.14 |
| 317.35 | 3.03 | 3.03 |
| 351.80 | 3.05 | 3.05 |
| 311.39 | 2.77 | 2.77 |
| 332.37 | 1.83 | 1.83 |
| 365.82 | 3.09 | 3.09 |
| 368.40 | 2.94 | 2.94 |
| 317.35 | 2.39 | 2.39 |
| 391.26 | 1.79 | 1.79 |
| 304.31 | 2.11 | 2.11 |
| 304.31 | 2.11 | 2.11 |
| 361.41 | 2.45 | 2.45 |
| 318.34 | 1.79 | 1.79 |
| 283.34 | 1.85 | 1.85 |