Basic Information
ID: ALA5148544
Type: Functional
Description: Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody addition and measured after 24 hrs in presence of NECA by ELISA
Organism: Homo sapiens
Cell type: T-cell
Activity Charts
Bioactivity
Activity Types for Assay ALA5148544
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.74 | 3.28 | 3.28 |
| 332.37 | 1.83 | 1.83 |
| 318.34 | 1.79 | 1.79 |
| 318.34 | 1.79 | 1.79 |
| 391.26 | 1.79 | 1.79 |
| 318.34 | 1.79 | 1.79 |