Basic Information
ID: ALA5149148
Type: Binding
Description: Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5149148
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 909.10 | 5.75 | 5.75 |
| 1044.31 | ||
| 961.26 | 8.12 | 8.12 |
| 1091.40 | ||
| 1017.37 | ||
| 1053.27 | ||
| 1076.39 | ||
| 1153.48 | ||
| 949.21 | 6.31 | 6.31 |
| 1091.40 | ||
| 1427.79 | ||
| 977.22 | 6.49 | 6.49 |
| 990.26 | 6.58 | 6.58 |
| 793.92 | 4.16 | 4.16 |
| 897.09 | 5.44 | 5.44 |
| 1238.54 | ||
| 1034.31 | ||
| 985.28 | 8.12 | 8.12 |
| 1190.54 | ||
| 883.06 | 5.40 | 5.40 |
| 1209.71 | ||
| 1256.55 | ||
| 1296.62 | ||
| 849.05 | 5.00 | 5.00 |
| 1134.43 | ||
| 1368.71 | ||
| 1160.47 | ||
| 915.08 | 5.58 | 5.58 |
| 1188.48 | ||
| 893.10 | 4.75 | 4.75 |
| 1162.44 | ||
| 1181.49 | ||
| 820.99 | 4.22 | 4.22 |
| 921.11 | 4.93 | 4.93 |
| 1112.38 | ||
| 1048.29 | ||
| 1082.40 | ||
| 1120.45 | ||
| 1196.50 | ||
| 1168.45 | ||
| 1182.43 | ||
| 1076.35 | ||
| 1270.65 | ||
| 976.28 | 7.06 | 7.06 |
| 1060.31 | ||
| 997.16 | 3.72 | 3.72 |
| 1011.19 | ||
| 1176.51 | ||
| 1005.27 | ||
| 1148.46 | ||
| 877.10 | 5.78 | 5.78 |
| 1125.38 | ||
| 969.15 | 3.24 | 3.24 |
| 1118.43 | ||
| 989.31 | 8.90 | 8.90 |
| 1097.37 | ||
| 1092.35 | ||
| 1168.45 | ||
| 1106.33 | ||
| 933.21 | 7.34 | 7.34 |
| 905.15 | 6.56 | 6.56 |
| 1208.58 | ||
| 1096.38 | ||
| 1104.40 | ||
| 1092.35 | ||
| 1133.44 | ||
| 1035.30 | ||
| 1254.58 | ||
| 1174.49 | ||
| 1324.67 | ||
| 977.26 | 7.09 | 7.09 |
| 1250.59 | ||
| 921.15 | 5.53 | 5.53 |
| 997.25 | 7.49 | 7.49 |
| 1148.46 | ||
| 991.24 | 7.18 | 7.18 |
| 1062.37 | ||
| 1130.32 | ||
| 1019.30 | ||
| 1132.37 | ||
| 996.27 | 7.36 | 7.36 |
| 1002.27 | ||
| 1086.39 | ||
| 1148.46 | ||
| 1004.29 | ||
| 1224.55 | ||
| 1191.48 | ||
| 1224.55 | ||
| 949.16 | 5.71 | 5.71 |
| 993.33 | 8.03 | 8.03 |
| 901.05 | 5.54 | 5.54 |
| 1125.42 | ||
| 1073.34 | ||
| 1135.42 |