Basic Information
ID: ALA5149302
Type: Binding
Description: Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase assessed as maximum relative efficacy at 3.3 uM incubated for 3 to 16 hrs by PathHunter chemiluminescence based assay relative to GW4064
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA5149302
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 496.65 | 6.72 | 6.72 |
| 567.71 | 7.51 | 7.51 |
| 539.65 | 6.73 | 6.73 |
| 557.64 | 7.18 | 7.18 |
| 536.72 | 6.81 | 6.81 |
| 535.69 | 6.90 | 6.90 |
| 556.11 | 7.24 | 7.24 |
| 539.65 | 6.73 | 6.73 |
| 553.68 | 7.12 | 7.12 |
| 539.65 | 6.89 | 6.89 |
| 534.70 | 7.35 | 7.35 |
| 520.67 | 7.36 | 7.36 |
| 567.71 | 7.51 | 7.51 |
| 553.68 | 7.12 | 7.12 |
| 567.71 | 7.51 | 7.51 |
| 540.70 | 6.87 | 6.87 |
| 549.72 | 7.37 | 7.37 |
| 521.66 | 6.59 | 6.59 |
| 539.65 | 6.73 | 6.73 |
| 539.65 | 6.73 | 6.73 |
| 546.67 | 6.46 | 6.46 |
| 526.68 | 6.21 | 6.21 |
| 567.71 | 7.51 | 7.51 |
| 553.75 | 6.78 | 6.78 |
| 522.69 | 6.82 | 6.82 |
| 553.68 | 7.12 | 7.12 |
| 535.69 | 6.98 | 6.98 |
| 568.71 | 6.76 | 6.76 |
| 547.70 | 7.12 | 7.12 |
| 553.68 | 7.12 | 7.12 |