Basic Information
ID: ALA5149637
Type: Binding
Description: Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells using FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by activation with ERK2 and substrate addition measured after 2 hrs by microfluidic chip based electrophoresis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5149637
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 196.21 | 1.82 | 1.82 |
| 263.13 | 4.33 | 4.33 |
| 289.30 | 2.02 | 2.02 |
| 450.50 | 3.05 | 3.05 |
| 310.54 | 2.63 | 2.63 |
| 230.66 | 2.47 | 2.47 |
| 229.67 | 3.07 | 3.07 |
| 266.09 | 2.72 | 2.72 |
| 230.66 | 2.47 | 2.47 |
| 255.67 | 2.34 | 2.34 |
| 230.66 | 2.47 | 2.47 |
| 248.65 | 2.61 | 2.61 |
| 244.69 | 2.78 | 2.78 |
| 265.10 | 3.12 | 3.12 |
| 196.21 | 1.82 | 1.82 |
| 255.67 | 2.34 | 2.34 |
| 231.65 | 1.86 | 1.86 |
| 298.66 | 3.49 | 3.49 |
| 276.75 | 3.19 | 3.19 |
| 266.09 | 2.52 | 2.52 |
| 265.10 | 3.33 | 3.33 |
| 244.69 | 2.78 | 2.78 |
| 248.65 | 2.61 | 2.61 |
| 255.67 | 2.34 | 2.34 |
| 244.69 | 2.78 | 2.78 |
| 309.55 | 3.23 | 3.23 |
| 264.12 | 3.73 | 3.73 |