Basic Information
ID: ALA5149645
Type: Binding
Description: Inhibition of N-terminal His-Smt-tagged MSK1 C-terminal kinase domain (414 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using FAM-PSKPAATRKRRWSAPESR-NH2 as substrate preincubated for 1 hr followed by substrate addition and measured after 70 mins in presence of 250 uM by ADP-Glo kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5149645
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 230.66 | 2.47 | 2.47 |
| 248.65 | 2.61 | 2.61 |
| 265.10 | 3.12 | 3.12 |
| 265.10 | 3.33 | 3.33 |
| 309.55 | 3.23 | 3.23 |