Basic Information
ID: ALA5149650
Type: Binding
Description: Inhibition of full-length N-terminal His-TEV-tagged inactive form of MSK1 (2 to 802 residues) (unknown origin) expressed in HEK293 cells assessed as constant reflecting half-time of enzyme self-activation at 20 times IC50 using ATXN1 peptide as substrate preincubated for 3 hrs followed by dilution with buffer and subsequent addition of substrate and ATP measured up to 7 hrs by jump dilution method (Rvb = 1.98 x 10^-4/s)
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5149650
K
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 196.21 | 1.82 | 1.82 |
| 230.66 | 2.47 | 2.47 |
| 266.09 | 2.52 | 2.52 |
| 265.10 | 3.33 | 3.33 |