Basic Information
ID: ALA5149726
Type: Binding
Description: Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ethyl isopropyl amiloride by BCECF-AM dye based fluorescence assay
Organism: Homo sapiens
Tissue: Kidney
Cell type: Kidney epithelial cell
Activity Charts
Bioactivity
Activity Types for Assay ALA5149726
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1145.07 | ||
| 371.29 | 3.22 | 3.22 |
| 1233.18 | ||
| 1145.07 | ||
| 1135.03 | ||
| 1119.03 | ||
| 1165.06 | ||
| 1165.06 | ||
| 1102.98 | ||
| 1223.14 | ||
| 1030.92 | ||
| 493.43 | 3.13 | 3.13 |
| 485.36 | 0.95 | 0.95 |
| 1253.17 | ||
| 1135.03 | ||
| 1030.92 | ||
| 1119.03 | ||
| 546.52 | 2.86 | 2.86 |
| 1086.99 | ||
| 1233.18 | ||
| 429.37 | 3.50 | 3.50 |
| 1165.06 | ||
| 1175.09 | ||
| 1116.03 | ||
| 485.36 | 0.95 | 0.95 |
| 1086.99 | ||
| 1119.03 | ||
| 1223.14 | ||
| 1179.08 | ||
| 856.72 | 6.74 | 6.74 |
| 1179.08 | ||
| 1090.97 | ||
| 1191.09 | ||
| 1179.08 | ||
| 429.33 | 2.93 | 2.93 |
| 1145.07 | ||
| 914.76 | 4.10 | 4.10 |
| 1253.17 | ||
| 1179.08 | ||
| 1002.87 | ||
| 1179.08 | ||
| 1102.98 | ||
| 485.36 | 0.95 | 0.95 |
| 1219.15 | ||
| 1090.97 | ||
| 493.35 | 3.42 | 3.42 |