Assay Report Card

Basic Information

ID: ALA5149766

Type: Functional

Description: In vivo inhibition of NEH3 in Sprague-Dawley rat assessed as reduction in sodium excretion in urine at 0.1 to 3 mg/kg, po administered via gavage measured after 16 hrs by ion chromatography

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1145.07
1165.06
1086.99
1119.03
1102.98
1219.15