Assay Report Card

Basic Information

ID: ALA5149793

Type: Binding

Description: Molecular glue activity at HA-tagged CLR4-CRBN/2HA-tagged PXR fused HiBiT-tagged FKBP12 (F36V) mutant (unknown origin) expressed in HepG2 cells assessed as induction of PXR degradation measured after 24 hrs by Nano-Glo HiBiT assay

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1049.18
666.694.344.34