Basic Information
ID: ALA5149881
Type: Binding
Description: Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21 Star (DE3) pLysS measured after 3 hrs by AlphaLISA assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5149881
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 813.45 | 7.88 | 7.88 |
| 399.43 | 3.24 | 3.24 |
| 527.44 | 6.24 | 6.24 |
| 427.46 | 3.78 | 3.78 |
| 521.42 | 6.18 | 6.18 |
| 439.49 | 3.65 | 3.65 |
| 477.36 | 5.19 | 5.19 |
| 476.37 | 5.14 | 5.14 |
| 387.44 | 4.54 | 4.54 |
| 463.33 | 5.23 | 5.23 |
| 517.43 | 6.07 | 6.07 |
| 486.53 | 5.93 | 5.93 |
| 345.40 | 4.16 | 4.16 |
| 442.52 | 5.42 | 5.42 |
| 442.52 | 5.42 | 5.42 |
| 477.46 | 4.84 | 4.84 |
| 516.40 | 6.01 | 6.01 |
| 492.37 | 6.01 | 6.01 |
| 434.48 | 3.51 | 3.51 |
| 521.42 | 6.04 | 6.04 |
| 488.36 | 4.41 | 4.41 |
| 483.57 | 6.23 | 6.23 |
| 510.39 | 6.38 | 6.38 |
| 510.39 | 6.38 | 6.38 |
| 504.38 | 6.18 | 6.18 |
| 449.30 | 5.14 | 5.14 |
| 520.43 | 6.79 | 6.79 |
| 520.43 | 6.79 | 6.79 |
| 427.46 | 3.78 | 3.78 |
| 521.42 | 6.18 | 6.18 |
| 497.64 | 7.32 | 7.32 |
| 596.53 | 8.18 | 8.18 |
| 504.38 | 5.64 | 5.64 |
| 521.42 | 6.18 | 6.18 |
| 534.45 | 7.03 | 7.03 |
| 491.39 | 6.01 | 6.01 |
| 537.54 | 6.77 | 6.77 |
| 443.91 | 4.30 | 4.30 |
| 442.52 | 5.42 | 5.42 |
| 491.39 | 6.00 | 6.00 |
| 504.43 | 5.97 | 5.97 |
| 491.39 | 5.53 | 5.53 |
| 423.49 | 3.95 | 3.95 |
| 520.43 | 6.65 | 6.65 |
| 445.52 | 5.93 | 5.93 |
| 519.62 | 5.43 | 5.43 |
| 521.42 | 6.18 | 6.18 |
| 506.40 | 6.40 | 6.40 |
| 504.38 | 6.15 | 6.15 |
| 478.35 | 5.62 | 5.62 |
| 527.44 | 6.24 | 6.24 |
| 409.47 | 3.64 | 3.64 |
| 505.42 | 5.97 | 5.97 |
| 454.46 | 3.55 | 3.55 |
| 477.46 | 4.66 | 4.66 |
| 521.42 | 6.18 | 6.18 |
| 423.49 | 3.95 | 3.95 |
| 519.44 | 6.36 | 6.36 |