Basic Information
ID: ALA5151318
Type: Binding
Description: Displacement of N-(4'-((17-(5,5-difluoro-7-(1H-pyrrol-2-yl)-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-15-oxo-4,7,10-trioxa-14-azaheptadecyl)carbamoyl)-4-(4-methylpiperazin-1-yl)-[1,1'-biphenyl]-3-yl)-6-hydroxy-4-(trifluoromethyl)nicotinamide tracer from N-/C-terminal NanoLuc-fused full-length WDR5 (unknown origin) transfected in HEK293T cells incubated for 2 hrs by NanoBRET assay
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA5151318
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1012.17 | ||
| 1072.22 | ||
| 1028.17 | ||
| 1019.04 | ||
| 1107.15 | ||
| 930.94 | 3.36 | 3.36 |
| 1040.22 | ||
| 1077.14 | ||
| 556.59 | 5.02 | 5.02 |
| 842.83 | 3.32 | 3.32 |
| 1165.25 | ||
| 1160.33 | ||
| 998.14 | 5.82 | 5.82 |
| 1209.30 | ||
| 1026.20 | ||
| 430.34 | 4.67 | 4.67 |
| 913.04 | 5.92 | 5.92 |
| 1121.19 | ||
| 944.98 | 6.69 | 6.69 |
| 984.11 | 5.43 | 5.43 |
| 1217.14 | ||
| 989.04 | 6.71 | 6.71 |
| 555.60 | 3.90 | 3.90 |
| 1185.09 | ||
| 1033.09 | ||
| 1060.21 | ||
| 874.88 | 5.01 | 5.01 |
| 1449.41 |