Basic Information
ID: ALA5151331
Type: Binding
Description: PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation at 1 uM incubated for 6 hrs in presence of Tert-Butyl 3'-(6-Hydroxy-4-(trifluoromethyl)-nicotinamido)-4'-(4-methylpiperazin-1-yl)-[1,1'-biphenyl]-4-carboxylate by qRT-PCR analysis relative to control
Organism: Homo sapiens
Cell type: MV4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA5151331
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1012.17 |