Basic Information
ID: ALA5151474
Type: Functional
Description: Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi protein recruitment by measuring maximum efficacy at 100 uM using furimazine as substrate measured for 45 mins by luminescence assay relative to histamine
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA5151474
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 111.15 | -0.09 | -0.09 |
| 211.33 | 1.58 | 1.58 |
| 1024.83 | -0.09 | -0.09 |
| 560.48 | 1.47 | 1.47 |
| 617.57 | 1.85 | 1.85 |
| 540.49 | 1.46 | 1.46 |
| 438.36 | 1.57 | 1.57 |
| 631.60 | 2.33 | 2.33 |
| 555.50 | 1.25 | 1.25 |
| 388.30 | 1.11 | 1.11 |
| 616.59 | 2.46 | 2.46 |
| 595.57 | 1.88 | 1.88 |
| 561.47 | 0.87 | 0.87 |
| 541.48 | 0.86 | 0.86 |
| 420.37 | 1.43 | 1.43 |