Basic Information
ID: ALA5151732
Type: Functional
Description: In vivo inhibition of LMP7 activity in tumor lysates of H2d Rag2 mouse xenografted with human U266B1 cells at 0.3 mg/kg, po administered once daily using (Ac-ANW)2R110 as substrate measured at 1 to 6 hrs post-last drug dosage by fluorescence intensity assay
Format: BAO_0000218
Organism: Mus musculus
Tissue: Neoplasm
Cell type: U-266
Subcellular Fraction: Lysates
Target: Unchecked(ALA612545)
Document: ALA5149996
In vivo inhibition of LMP7 activity in tumor lysates of H2d Rag2 mouse xenografted with human U266B1 cells at 0.3 mg/kg, po administered once daily using (Ac-ANW)2R110 as substrate measured at 1 to 6 hrs post-last drug dosage by fluorescence intensity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5151732
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.16 |