Assay Report Card

Basic Information

ID: ALA5151744

Type: Functional

Description: Antagonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as inhibition of LysoPalloT-NH-C3-ph-m-O-C11-induced AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay relative to control

Organism: Mus musculus

Cell type: HEK293FT

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
573.665.255.25
616.694.124.12
574.653.813.81
616.694.384.38
616.694.124.12
644.744.764.76
602.663.733.73
616.694.124.12
559.644.864.86
558.654.284.28
670.785.295.29
616.693.823.82
586.664.764.76
630.724.514.51
559.644.864.86
644.744.904.90
664.735.025.02
616.694.124.12
678.765.335.33
616.694.124.12
720.846.326.32