Basic Information
ID: ALA5152402
Type: Binding
Description: Inhibition of human NTCP mediated TCA uptake in HEK293 cells overexpressing NTCP preincubated for 5 mins followed by substrate addition and measured after 10 mins using [3H] taurocholic acid as substrate by liquid scintillation counter analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5152402
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.60 | 3.12 | 3.12 |
| 488.63 | 3.48 | 3.48 |
| 476.61 | 3.02 | 3.02 |