Basic Information
ID: ALA5152446
Type: Binding
Description: Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential at 100 nM by two-electrode voltage clamp method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Oocyte
Target: Neuronal acetylcholine receptor; alpha9/alpha10(ALA2109238)
Document: ALA5150017
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential at 100 nM by two-electrode voltage clamp method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5152446
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1778.01 | ||
| 1630.79 | ||
| 1678.88 | ||
| 1690.93 | ||
| 1663.91 | ||
| 1771.02 | ||
| 1612.87 | ||
| 1633.88 | ||
| 1631.87 | ||
| 1613.85 | ||
| 1683.95 | ||
| 1728.00 | ||
| 1672.88 | ||
| 1669.92 | ||
| 1613.85 | ||
| 1682.96 | ||
| 1643.88 | ||
| 1600.81 | ||
| 1601.80 | ||
| 1601.80 | ||
| 1613.85 | ||
| 1627.88 | ||
| 1628.86 | ||
| 1627.88 | ||
| 1615.82 | ||
| 1671.89 |