Basic Information
ID: ALA5152449
Type: Binding
Description: Antagonist activity at human alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential in presence of BAPTA-AM at 100 nM by two-electrode voltage clamp method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Oocyte
Target: Neuronal acetylcholine receptor; alpha4/beta2(ALA1907589)
Document: ALA5150017
Antagonist activity at human alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential in presence of BAPTA-AM at 100 nM by two-electrode voltage clamp method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5152449
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1613.85 |