Basic Information
ID: ALA5152635
Type: Binding
Description: Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assay
Organism: Homo sapiens
Cell type: RPMI-8226
Activity Charts
Bioactivity
Activity Types for Assay ALA5152635
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.56 | 4.13 | 4.13 |
| 441.59 | 5.97 | 5.97 |
| 441.59 | 5.97 | 5.97 |
| 424.59 | 5.22 | 5.22 |
| 473.66 | 6.98 | 6.98 |
| 442.59 | 2.65 | 2.65 |
| 260.34 | 0.62 | 0.62 |
| 441.58 | 4.37 | 4.37 |
| 437.63 | 6.14 | 6.14 |
| 448.61 | 5.70 | 5.70 |
| 440.59 | 4.52 | 4.52 |
| 437.63 | 6.14 | 6.14 |
| 481.64 | 5.62 | 5.62 |
| 454.62 | 4.91 | 4.91 |
| 424.59 | 5.22 | 5.22 |
| 454.57 | 3.70 | 3.70 |
| 448.61 | 5.70 | 5.70 |
| 459.58 | 6.11 | 6.11 |
| 438.58 | 4.29 | 4.29 |
| 438.62 | 5.53 | 5.53 |
| 414.53 | 2.03 | 2.03 |
| 423.56 | 5.32 | 5.32 |
| 412.54 | 3.74 | 3.74 |
| 375.52 | 3.47 | 3.47 |
| 445.50 | 1.63 | 1.63 |
| 505.73 | 7.48 | 7.48 |
| 424.59 | 5.22 | 5.22 |
| 452.61 | 4.53 | 4.53 |
| 423.60 | 5.83 | 5.83 |
| 453.63 | 5.84 | 5.84 |
| 424.59 | 5.22 | 5.22 |
| 425.58 | 4.62 | 4.62 |
| 424.59 | 5.22 | 5.22 |
| 452.60 | 4.23 | 4.23 |
| 441.59 | 5.97 | 5.97 |
| 364.45 | 2.18 | 2.18 |
| 418.49 | 1.87 | 1.87 |
| 388.56 | 4.38 | 4.38 |
| 364.49 | 2.58 | 2.58 |
| 424.59 | 5.22 | 5.22 |
| 437.63 | 6.14 | 6.14 |
| 453.63 | 5.84 | 5.84 |
| 436.56 | 3.74 | 3.74 |
| 500.69 | 6.89 | 6.89 |
| 390.54 | 3.17 | 3.17 |
| 452.65 | 5.84 | 5.84 |