Basic Information
ID: ALA5152846
Type: Binding
Description: PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM preincubated with MG-132 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HL-60
Target: VHL/FLT3(ALA4523735)
Document: ALA5150032
PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM preincubated with MG-132 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5152846
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 858.01 | 4.27 | 4.27 |