Assay Report Card

Basic Information

ID: ALA5152848

Type: Binding

Description: PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HL-60

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
858.014.274.27