PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 20 uM preincubated with VHL032 for 1 hrs followed by...

Basic Information

ID: ALA5152848

Type: Binding

Description: PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HL-60

Target:  VHL/KIT(ALA4523731)

Document:  ALA5150032

PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
858.014.274.27