Basic Information
ID: ALA5152973
Type: Binding
Description: Inhibition of human mitochondrial HSP60 expressed in Escherichia coli Rosetta 2 (DE3) cells/human mitochondrial HSP10 expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells assessed as inhibition of GroEL/ES-mediated dMDH refolding by reporter analysis
Organism: Homo sapiens
Subcellular Fraction: Mitochondria
Activity Charts
Bioactivity
Activity Types for Assay ALA5152973
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 208.26 | 3.58 | 3.58 |
| 224.26 | 3.29 | 3.29 |
| 224.26 | 3.29 | 3.29 |
| 238.29 | 3.59 | 3.59 |
| 238.29 | 3.59 | 3.59 |
| 265.31 | 3.54 | 3.54 |
| 211.26 | 2.62 | 2.62 |
| 210.28 | 3.50 | 3.50 |
| 223.28 | 3.16 | 3.16 |
| 255.27 | 3.13 | 3.13 |
| 213.24 | 2.76 | 2.76 |
| 362.34 | 4.34 | 4.34 |
| 285.25 | 2.90 | 2.90 |
| 323.37 | 4.49 | 4.49 |
| 333.41 | 4.90 | 4.90 |
| 310.31 | 3.45 | 3.45 |
| 378.41 | 4.80 | 4.80 |
| 210.28 | 3.43 | 3.43 |
| 317.34 | 4.43 | 4.43 |
| 327.38 | 4.84 | 4.84 |
| 372.38 | 4.74 | 4.74 |