Basic Information
ID: ALA5153037
Type: Binding
Description: Inhibition of EGFR (unknown origin) L858R/T790M mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5153037
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.91 | 4.28 | 4.28 |
| 499.62 | 4.51 | 4.51 |
| 542.69 | 3.77 | 3.77 |
| 431.88 | 3.84 | 3.84 |
| 387.82 | 3.82 | 3.82 |
| 387.82 | 3.82 | 3.82 |
| 365.43 | 4.71 | 4.71 |
| 399.88 | 5.37 | 5.37 |
| 449.87 | 3.98 | 3.98 |
| 405.81 | 3.96 | 3.96 |
| 353.38 | 3.17 | 3.17 |
| 399.88 | 5.37 | 5.37 |
| 353.38 | 3.17 | 3.17 |
| 387.82 | 3.82 | 3.82 |
| 387.82 | 3.82 | 3.82 |
| 375.79 | 3.95 | 3.95 |
| 387.82 | 3.82 | 3.82 |
| 431.88 | 3.84 | 3.84 |
| 431.88 | 3.84 | 3.84 |
| 399.88 | 5.37 | 5.37 |
| 399.88 | 5.37 | 5.37 |
| 387.82 | 3.82 | 3.82 |
| 397.43 | 3.19 | 3.19 |
| 387.82 | 3.82 | 3.82 |
| 431.88 | 3.84 | 3.84 |
| 335.72 | 3.59 | 3.59 |
| 417.87 | 5.51 | 5.51 |