Assay Report Card

Basic Information

ID: ALA5153073

Type: Binding

Description: Inhibition of ERK1/2 phosphorylation in mouse BaF3 cells harboring L858R mutant assessed as ERK1/2 phosphorylation at 10 to 1000 nM incubated for 8 hrs by Western blot analysis

Organism: Mus musculus

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
449.873.983.98
375.793.953.95
431.883.843.84
335.723.593.59