Basic Information
ID: ALA5153076
Type: Binding
Description: Inhibition of ERK1/2 phosphorylation in mouse BaF3 cells harboring L858R/C797S double mutant assessed as ERK1/2 phosphorylation at 10 to 1000 nM incubated for 8 hrs by Western blot analysis
Organism: Mus musculus
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA5153076
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.87 | 3.98 | 3.98 |
| 375.79 | 3.95 | 3.95 |
| 431.88 | 3.84 | 3.84 |
| 335.72 | 3.59 | 3.59 |