Basic Information
ID: ALA5153159
Type: Functional
Description: Inhibition of caspase-1 mediated pyroptosis in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as live cells at 10 uM pretreated for 24 hrs followed by LPS addition for 3 hrs and further incubated for 1 hr with ATP by caspase-1/PI staining based flow cytometry analysis (Rvb = 43.3%)
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5153159
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.51 | 7.36 | 7.36 |
| 353.35 | 3.33 | 3.33 |