ID: ALA5153166
Type: Functional
Description: Inhibition of caspase-1 mediated pyroptosis in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as dead cells at 20 uM pretreated for 24 hrs followed by LPS addition for 3 hrs and further incubated for 1 hr with ATP by caspase-1/PI staining based flow cytometry analysis (Rvb = 22.5%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Unchecked(ALA612545)
Document: ALA5150046
Inhibition of caspase-1 mediated pyroptosis in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as dead cells at 20 uM pretreated for 24 hrs followed by LPS addition for 3 hrs and further incubated for 1 hr with ATP by caspase-1/PI staining based flow cytometry analysis (Rvb = 22.5%): 1
Bioactivity
Activity Types for Assay ALA5153166
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
353.35 | 3.33 | 3.33 |