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Inhibition of caspase-1 mediated pyroptosis in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as dead cells at 20 uM pretreated for 24 ...

Basic Information

ID: ALA5153166

Type: Functional

Description: Inhibition of caspase-1 mediated pyroptosis in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as dead cells at 20 uM pretreated for 24 hrs followed by LPS addition for 3 hrs and further incubated for 1 hr with ATP by caspase-1/PI staining based flow cytometry analysis (Rvb = 22.5%)

Format: BAO_0000219

Organism: Homo sapiens

Cell type: THP-1

Target:  Unchecked(ALA612545)

Document:  ALA5150046

Inhibition of caspase-1 mediated pyroptosis in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as dead cells at 20 uM pretreated for 24 hrs followed by LPS addition for 3 hrs and further incubated for 1 hr with ATP by caspase-1/PI staining based flow cytometry analysis (Rvb = 22.5%): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
353.353.333.33