Basic Information
ID: ALA5153172
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS/ATP induced PMA-differentiated human THP-1 cells assessed as reduction in pro-IL-1beta expression pretreated for 24 hrs followed by LPS addition for 3 hrs and further incubated for 1 hr with ATP by Western blot analysis
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5153172
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.35 | 3.33 | 3.33 |