Basic Information
ID: ALA5153564
Type: Binding
Description: Inhibition of recombinant human HDAC3 using p53 (Ac-RHKK(Acetyl)-AMC) as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence based analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone deacetylase 3(ALA1829)
Document: ALA5150060
Inhibition of recombinant human HDAC3 using p53 (Ac-RHKK(Acetyl)-AMC) as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence based analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5153564
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.50 | 1.92 | 1.92 |
| 319.80 | 2.39 | 2.39 |
| 285.35 | 1.73 | 1.73 |
| 449.60 | 3.11 | 3.11 |
| 335.41 | 2.89 | 2.89 |
| 367.49 | 3.80 | 3.80 |
| 354.24 | 3.04 | 3.04 |
| 319.80 | 2.39 | 2.39 |
| 339.44 | 3.02 | 3.02 |
| 398.51 | 2.54 | 2.54 |
| 291.40 | 2.14 | 2.14 |
| 356.43 | 1.37 | 1.37 |
| 249.31 | 0.97 | 0.97 |
| 325.41 | 2.63 | 2.63 |
| 435.58 | 3.09 | 3.09 |
| 327.43 | 2.90 | 2.90 |
| 463.63 | 3.15 | 3.15 |
| 299.38 | 2.12 | 2.12 |
| 377.49 | 4.06 | 4.06 |
| 449.60 | 3.14 | 3.14 |
| 341.46 | 2.95 | 2.95 |
| 278.36 | -0.13 | -0.13 |
| 325.46 | 4.11 | 4.11 |
| 353.47 | 3.41 | 3.41 |