Basic Information
ID: ALA5154067
Type: Binding
Description: Inhibition of recombinant full length C-terminal His/Flag-tagged human HDAC1 (1 to 482 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based microplate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5154067
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 738.75 | 0.44 | 0.44 |
| 796.83 | 0.85 | 0.85 |
| 840.88 | 0.86 | 0.86 |
| 875.86 | 1.64 | 1.64 |
| 769.79 | 3.53 | 3.53 |
| 839.90 | 0.90 | 0.90 |
| 694.70 | 0.42 | 0.42 |
| 874.88 | 1.68 | 1.68 |
| 734.81 | 2.75 | 2.75 |
| 831.81 | 1.63 | 1.63 |