Basic Information
ID: ALA5154218
Type: Binding
Description: Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured every 10 sec for 10 mins by FRET assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5154218
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.53 | 1.10 | 1.10 |
| 369.21 | 1.33 | 1.33 |
| 492.35 | 4.51 | 4.51 |
| 440.35 | 2.98 | 2.98 |
| 517.41 | 4.71 | 4.71 |
| 492.38 | 3.86 | 3.86 |
| 570.50 | 4.24 | 4.24 |
| 476.81 | 2.99 | 2.99 |
| 563.23 | ||
| 475.40 | 4.10 | 4.10 |
| 452.36 | 3.08 | 3.08 |
| 491.24 | 3.78 | 3.78 |
| 442.34 | 3.87 | 3.87 |
| 481.43 | 4.16 | 4.16 |
| 481.23 | 4.19 | 4.19 |
| 436.36 | 3.41 | 3.41 |
| 536.51 | 4.86 | 4.86 |
| 531.49 | 5.31 | 5.31 |
| 553.86 | 5.26 | 5.26 |
| 530.38 | 3.28 | 3.28 |
| 422.34 | 3.02 | 3.02 |
| 537.40 | 4.75 | 4.75 |
| 502.42 | 4.27 | 4.27 |
| 428.34 | 2.38 | 2.38 |
| 482.77 | 4.22 | 4.22 |
| 424.35 | 3.57 | 3.57 |
| 525.68 | 4.35 | 4.35 |
| 460.41 | 3.34 | 3.34 |
| 437.35 | 3.30 | 3.30 |
| 570.13 | 4.50 | 4.50 |
| 509.37 | 4.20 | 4.20 |
| 446.79 | 3.63 | 3.63 |
| 508.45 | 4.33 | 4.33 |