ID: ALA5155266
Type: ADME
Description: Metabolic stability in human hepatocytes assessed as intrinsic clearance per 10^6 cells at 0.5 uM by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: Hepatocyte
Bioactivity
Activity Types for Assay ALA5155266
CLH
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
412.50 | 3.86 | 3.86 |
427.51 | 3.44 | 3.44 |
565.58 | 2.78 | 2.78 |
553.65 | 1.60 | 1.60 |
456.55 | 3.50 | 3.50 |
581.58 | 1.29 | 1.29 |
473.54 | 1.66 | 1.66 |
635.67 | 3.07 | 3.07 |
446.51 | 2.63 | 2.63 |
484.48 | 3.64 | 3.64 |
508.60 | 2.42 | 2.42 |
430.51 | 2.93 | 2.93 |
537.52 | 2.15 | 2.15 |
416.49 | 2.54 | 2.54 |
522.92 | 3.04 | 3.04 |
446.51 | 2.17 | 2.17 |
528.54 | 3.26 | 3.26 |
487.61 | 3.04 | 3.04 |
609.63 | 2.22 | 2.22 |
390.45 | 2.15 | 2.15 |
520.62 | 2.56 | 2.56 |
551.55 | 2.54 | 2.54 |
444.54 | 3.32 | 3.32 |
488.59 | 3.07 | 3.07 |
609.63 | 2.68 | 2.68 |
563.56 | 2.54 | 2.54 |
581.58 | 1.76 | 1.76 |
460.54 | 2.29 | 2.29 |
534.64 | 2.95 | 2.95 |
509.59 | 1.53 | 1.53 |
458.57 | 3.75 | 3.75 |
500.48 | 3.52 | 3.52 |
450.93 | 3.28 | 3.28 |
572.59 | 4.05 | 4.05 |
502.62 | 3.46 | 3.46 |
484.48 | 3.48 | 3.48 |
474.57 | 2.68 | 2.68 |
482.49 | 3.23 | 3.23 |
502.62 | 3.46 | 3.46 |
554.48 | 2.99 | 2.99 |
494.58 | 2.03 | 2.03 |
470.54 | 3.03 | 3.03 |
526.54 | 2.83 | 2.83 |
455.52 | 3.44 | 3.44 |
460.54 | 2.56 | 2.56 |
509.59 | 2.00 | 2.00 |
516.60 | 3.41 | 3.41 |
474.57 | 2.54 | 2.54 |
544.53 | 3.13 | 3.13 |
522.63 | 2.81 | 2.81 |
581.70 | 2.53 | 2.53 |
448.53 | 2.15 | 2.15 |
554.60 | 3.76 | 3.76 |