Basic Information
ID: ALA5155267
Type: ADME
Description: Metabolic stability in rat hepatocyte assessed as intrinsic clearance per 10^8 cells at 0.5 uM by LC-MS/MS analysis
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Hepatocyte
Target: ADMET(ALA612558)
Document: ALA5154644
Metabolic stability in rat hepatocyte assessed as intrinsic clearance per 10^8 cells at 0.5 uM by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5155267
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.50 | 3.86 | 3.86 |
| 427.51 | 3.44 | 3.44 |
| 565.58 | 2.78 | 2.78 |
| 553.65 | 1.60 | 1.60 |
| 456.55 | 3.50 | 3.50 |
| 581.58 | 1.29 | 1.29 |
| 473.54 | 1.66 | 1.66 |
| 635.67 | 3.07 | 3.07 |
| 446.51 | 2.63 | 2.63 |
| 484.48 | 3.64 | 3.64 |
| 508.60 | 2.42 | 2.42 |
| 430.51 | 2.93 | 2.93 |
| 537.52 | 2.15 | 2.15 |
| 416.49 | 2.54 | 2.54 |
| 522.92 | 3.04 | 3.04 |
| 446.51 | 2.17 | 2.17 |
| 528.54 | 3.26 | 3.26 |
| 487.61 | 3.04 | 3.04 |
| 609.63 | 2.22 | 2.22 |
| 390.45 | 2.15 | 2.15 |
| 520.62 | 2.56 | 2.56 |
| 551.55 | 2.54 | 2.54 |
| 444.54 | 3.32 | 3.32 |
| 488.59 | 3.07 | 3.07 |
| 609.63 | 2.68 | 2.68 |
| 563.56 | 2.54 | 2.54 |
| 581.58 | 1.76 | 1.76 |
| 460.54 | 2.29 | 2.29 |
| 534.64 | 2.95 | 2.95 |
| 509.59 | 1.53 | 1.53 |
| 458.57 | 3.75 | 3.75 |
| 500.48 | 3.52 | 3.52 |
| 450.93 | 3.28 | 3.28 |
| 572.59 | 4.05 | 4.05 |
| 502.62 | 3.46 | 3.46 |
| 484.48 | 3.48 | 3.48 |
| 474.57 | 2.68 | 2.68 |
| 482.49 | 3.23 | 3.23 |
| 502.62 | 3.46 | 3.46 |
| 554.48 | 2.99 | 2.99 |
| 494.58 | 2.03 | 2.03 |
| 470.54 | 3.03 | 3.03 |
| 526.54 | 2.83 | 2.83 |
| 455.52 | 3.44 | 3.44 |
| 460.54 | 2.56 | 2.56 |
| 509.59 | 2.00 | 2.00 |
| 516.60 | 3.41 | 3.41 |
| 474.57 | 2.54 | 2.54 |
| 544.53 | 3.13 | 3.13 |
| 522.63 | 2.81 | 2.81 |
| 581.70 | 2.53 | 2.53 |
| 448.53 | 2.15 | 2.15 |
| 554.60 | 3.76 | 3.76 |