Basic Information
ID: ALA5155869
Type: Binding
Description: Activation of human recombinant IDE assessed as fold change in activation efficacy using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-trp as substrate at 100 uM incubated for 10 mins followed by substrate addition and measured after 20 mins by fluorescence spectrophotometer analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Insulin-degrading enzyme(ALA1293287)
Document: ALA5154655
Activation of human recombinant IDE assessed as fold change in activation efficacy using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-trp as substrate at 100 uM incubated for 10 mins followed by substrate addition and measured after 20 mins by fluorescence spectrophotometer analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5155869
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.55 | 3.01 | 3.01 |
| 456.59 | 3.67 | 3.67 |
| 338.45 | 3.39 | 3.39 |
| 450.56 | 3.60 | 3.60 |
| 450.56 | 3.60 | 3.60 |
| 469.57 | 3.21 | 3.21 |
| 328.39 | 2.30 | 2.30 |
| 326.40 | 2.30 | 2.30 |
| 436.54 | 3.21 | 3.21 |
| 451.55 | 3.00 | 3.00 |
| 444.51 | 3.40 | 3.40 |
| 388.49 | 2.17 | 2.17 |
| 464.59 | 3.95 | 3.95 |
| 451.55 | 3.00 | 3.00 |
| 500.62 | 4.76 | 4.76 |
| 456.59 | 3.67 | 3.67 |
| 444.51 | 3.40 | 3.40 |
| 314.41 | 2.77 | 2.77 |
| 451.55 | 2.15 | 2.15 |
| 464.59 | 3.99 | 3.99 |
| 422.51 | 2.82 | 2.82 |
| 310.40 | 2.89 | 2.89 |
| 436.54 | 3.21 | 3.21 |
| 450.56 | 3.60 | 3.60 |
| 454.56 | 2.34 | 2.34 |
| 451.55 | 2.15 | 2.15 |
| 450.56 | 3.67 | 3.67 |
| 324.43 | 2.90 | 2.90 |
| 420.54 | 4.12 | 4.12 |