Basic Information
ID: ALA5155992
Type: Binding
Description: Substrate activity at P-gp in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as rhodamine 123 accumulation at 4 uM incubated for 30 mins in presence of rhodamine 123 by flow cytometry analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H460
Target: P-glycoprotein 1(ALA4302)
Document: ALA5154660
Substrate activity at P-gp in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as rhodamine 123 accumulation at 4 uM incubated for 30 mins in presence of rhodamine 123 by flow cytometry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5155992
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.52 | 6.80 | 6.80 |
| 591.53 | 6.53 | 6.53 |